If you're in Istaravshan and interested in visiting museums, a great place to start is the Museum of Archeology and Fortification. It features artifacts from ancient settlements and fortresses in the region, as well as exhibits about the history and culture of Tajikistan. Another museum of interest in the area is the Museum of Sadriddin Ayni, dedicated to the famous Tajik writer and philosopher.
If you would like to explore more museums in the region, you may also want to consider visiting the Museum of Antiquities in Khujand or the Museum of Local Lore in Dushanbe, both of which are within driving distance from Istaravshan.